Opening up with Do I Wanna Know? off album AM, lead singer Alex Turner strutted around the stage like the love-child of Elvis Presley and Kenickie from Grease.
Smoke descended on the audience as fans lit flares but once more this weekend sound issues proved problematic.
Certain sections of the crowd struggled with the audio being too quiet and with songs like Brianstorm, which should blast off your face with heavy drums, deep bass and a heavy riff, some of the audience felt a bit short changed.
Having earlier played a surprise six-song acoustic set on the BBC Introducing Stage, folk rocker Jake Bugg stepped up to the Main Stage.
Saying very little but delivering a lot, Bugg treated the audience to an extremely tight set and more than justified his billing.
Earlier on, Irish singer/songwriter Hozier wowed the Festival Republic Stage crowd with his incredible voice and Brooklyn's American Authors performed at their first British festival playing, among others, their top 20 hit Best Day Of My Life.
If festival-goers hadn't properly recovered from their hangovers and sleepless night following day one of the festival, The Hives really took the main stage by the scruff of the neck and woke everyone up.
Dressed in white suits with black ties, the Swedish rockers turned up the volume a few notches, drawing in a surprisingly large crowd for the mid-afternoon slot.
Lead singer Howlin' Pelle Almqvist went right out into the crowd for many of the songs, encouraging the crowd to chip in with the choruses of staple hits Hate To Say I Told You So, Main Offender and Walk Idiot Walk.
To follow, Californian trio Foster The People proved to be the ideal accompaniment to the evening sun, churning off hits from their two top-40 albums Torches and Supermodel.
As the sun went down the party atmosphere rose when London indie rockers Bombay Bicycle Club played to a bulging NME/BBC Radio One stage.
Reeling off catalogue favourites such as Always Like This, Carry Me and Shuffle, the band had the crowd in the palm of its hand, with the tent becoming a sea of dancing and body popping en masse.
Coupled with quirky animations on the background screen, the quartet excited fans further by proclaiming the stage to be the "best of any festival in the world".
Once more the rain stayed off for the most part. Black clouds threatened to open up but, despite a wet hour, Saturday stayed dry.