A total of 57 people died on roads in the Thames Valley in 2013 in 55 fatal collisions, which has dropped by more than a quarter from 78 fatal collisions in 2012.
The latest figures are the lowest ever recorded by Thames Valley Police since its formation in 1968.
The Thames Valley Police joint operations unit for roads policing works to reduce the number of deaths, injuries and crime on the roads. The number of deaths has fallen dramatically since 2004, when 129 were recorded.
Chief inspector Henry Parsons, head of the Thames Valley Police joint operations unit for roads policing, said: “There are many factors which may have contributed to the reduction in fatal road traffic collisions.
“Our officers conduct targeted enforcement to both educate and, where appropriate, prosecute offenders. Research shows that through targeting key offences such as speed, mobile phone use, not wearing a seatbelt and drink/drug driving, we can make the roads a safer place for everyone who uses them.”
Of the 57 deaths in 2013, 17 were in Berkshire, 23 in Buckinghamshire and 17 in Oxfordshire.
Chief Inspector Parsons also attributed the low number to road safety campaigns, and efficient police work to reduce the factors which lead to collisions.
He said: “We also run a number of campaigns such as Bike Safe and Safe Drive Stay Alive which are having an impact together with the work we conduct with our partner agencies.
“Our officers will continue to carry out this work 24/7 to continue to reduce the factors which contribute to collisions.
“Too many people continue to die on the roads despite every effort and every one of these figures is a person who has died on the road network and who has not returned home to their loved ones.”