The offenders removed a cash register and money from another till from The Village Inn pub in Yorktown Road, Sandhurst.
They entered by the conservatory at the rear of the property between 6am and 6.45am on Tuesday (January 1).
Thames Valley Police is appealing for witnesses, and anyone with any information should call PC Clare Hickman of Bracknell police station via the 24-hour Thames Valley Police Enquiry Line on 101.
If you don't want to speak directly to the police you can contact the independent charity Crimestoppers anonymously on 0800 555 111 or online at crimestoppers-uk.org.
No personal details are taken, information is not traced or recorded and you will not go to court.